Contents
Epstein–Barr Virus (EBV)
Overview
Epstein–Barr virus seroconversion—better known as a first EBV infection or “glandular fever”—usually causes sore throat, swollen glands and fatigue. For most adults it settles within weeks, but EBV can be linked to a lifetime risk of multiple sclerosis (MS). Understanding that risk and optimising recovery can protect long‑term brain health.
At The Royal Buckinghamshire Hospital, Aylesbury you can access fast laboratory testing, consultant‑led neurological advice, on‑site imaging when needed and personalised rehabilitation to rebuild energy—without NHS waiting lists.
Why Early Assessment Matters — Including MS Risk
- Large population studies suggest prior EBV infection is strongly associated with later MS. While the absolute risk remains low, monitoring neurological symptoms and lifestyle risk factors (vitamin D, smoking, weight) is sensible.
- Severe or prolonged post‑viral fatigue can lead to de‑conditioning, mood change and work absence—early rehab speeds recovery.
- EBV can inflame the liver, spleen or nerves; timely bloods and imaging pick up complications.
Symptoms You Might Notice
- Sore throat, painful swallowing and swollen tonsils
- Enlarged neck glands, fever and night sweats
- Profound tiredness and muscle aches that linger for weeks
- Headache, loss of appetite or mild jaundice
- Occasionally a rash after antibiotics such as amoxicillin
- Rarely, tingling, weakness or visual symptoms that warrant neurological review
How EBV Spreads
- Saliva contact (kissing, shared drinks or cutlery)
- Less commonly via blood transfusion or organ transplant
- The virus remains dormant for life and can reactivate without symptoms
When To Seek Medical Advice
Call 01296 678 800 if you have:
- Persistent sore throat and fatigue beyond two weeks
- Marked swelling under the left ribs (possible enlarged spleen)
- Yellowing of the eyes/skin, dark urine or pale stools
- New neurological symptoms such as numbness, blurred vision or weakness (possible demyelination—needs urgent assessment)
Go to A&E or dial 999 for sudden severe abdominal pain, difficulty breathing or confusion.
How We Diagnose And Monitor EBV
- Consultant Medical/Neurology Review – full history, examination and discussion of MS risk in our Neurology Department.
- Rapid Laboratory Testing – EBV serology (VCA IgM/IgG, EBNA), full blood count, liver enzymes and inflammatory markers via our Blood‑Testing Service, typically back within 24 hours.
- Imaging When Indicated – abdominal ultrasound for spleen/liver issues or CT/MRI (CT on site in our CT Suite if neurological red flags appear.
- Follow‑Up Plan – review at 4–6 weeks to confirm recovery, address lingering fatigue and set lifestyle targets to reduce MS risk (vitamin D, exercise, smoking cessation).
Treatment And Support
- Symptom Control – analgesia, hydration guidance and graded rest (not total bed rest).
- Activity Pacing & Rehabilitation – physiotherapy and occupational therapy through our Rehabilitation Service to rebuild stamina safely.
- Nutrition & Immune Support – anti‑inflammatory, Mediterranean‑style plans and vitamin D optimisation with our Dietetic Team.
- Return‑To‑Work Planning – phased schedules, fatigue management and ergonomic advice.
- Neurology Surveillance – rapid access back to clinic if new sensory, visual or balance issues emerge that could hint at demyelinating disease.
(Antivirals have limited benefit in uncomplicated EBV; care focuses on supportive management and complication surveillance.)
Reducing Long‑Term MS Risk: Practical Steps
- Stop smoking and limit alcohol intake
- Maintain vitamin D within the healthy range (we test and supplement if needed)
- Keep blood pressure, cholesterol and weight in check with help from our Cardiology Department and Private GP Service
- Stay physically active—regular aerobic and resistance exercise supports brain and immune health
Why Choose The Royal Buckinghamshire Hospital?
- Appointments usually available within one week
- Fast, co‑located blood tests and CT imaging for quick answers
- Consultant‑delivered clinics; no junior‑doctor hand‑offs
- Integrated neurology, rehabilitation, dietetics and cardiology services on site
- Flexible evening and Saturday slots, plus virtual follow‑ups
- Free parking and private ensuite rooms with easy access from Oxford, Milton Keynes and London
Frequently Asked Questions
Will I Definitely Get MS After EBV?
No. Most people with EBV never develop MS. The infection is one factor among many; controlling others (vitamin D, smoking, weight) helps reduce risk.
How Long Will Fatigue Last?
Many feel better within 2–6 weeks, but some experience fatigue for months. Structured rehab and pacing strategies shorten recovery.
Can I Exercise During Recovery?
Yes—gentle, graded activity is better than complete rest. Our physiotherapists tailor a plan to avoid boom‑and‑bust cycles.
Feel Better Now, Protect Your Future Brain Health
Call 01296 678 800 or enquire online to book your EBV assessment, MS‑risk review and personalised recovery plan.
23 July 2025